NMN Wonderfeel Capsul 60 vegcaps

NMN is a patented solution to aging. Using a multi-targeted approach to defend and slow down biological aging at the cellular level.

NMN helps increasing energy levels, restoring skin elasticity, while optimizing organ health, and cognition. *

Taken orally, NMN is rapidly absorbed and converted to NAD+ (Nicotinamide adenine dinucleotide). In numerous studies, supplementation with NMN has increased NAD+ biosynthesis, suppressed age-related adipose tissue inflammation, enhanced insulin secretion and insulin action, improved mitochondrial function, improved neuronal function in the brain, and more. 1

Nicotinamide mononucleotide (NMN) is one of the main precursors of nicotinamide adenine dinucleotide (NAD+), an essential enzyme for various critical cell functions, including metabolism, DNA repair, cell growth and survival. The process of aging overtime results in function defects in organ function and tissue health, resulting in a cascade of different health issues and poorer functionality. This is triggered by a decrease in systemic NAD+ biosynthesis. An increase in intracellular levels of NAD+ triggers shifts that enhance survival, including boosting energy production and upregulating cellular repair. *

NMN can suppress the expression of a broad set of genes in induced pluripotent stem cell-derived retinal pigment epithelium (iPS-RPE) cells that may contribute to age-related macular degeneration (AMD). 2

Decreased serum levels of nicotinamide (NAM), which is a precursor of NAD, has also been documented in glaucoma patients (and in the retina), 3 as well as mitochondrial (our cell’s energy batteries) abnormalities that lead up to it have been identified in both animal models 4 and glaucoma patients. 5 An increase in mitochondrial size and motility, in addition to a simultaneous dampening of the action potential firing frequency, has also been documented related to mitochondrial functioning.

Product Information:
60 Vegan Capsules per Bottle (1 month supply)
Ingredients:
1000mg NMN per Serving (Two Capsules)
Non-GMO, vegan friendly, does not contain preservatives.
Rice hull powder added for stabilization.

Our capsule shells are made from vegetable cellulose and are 100% vegan.

Recommended Usage:
Take two capsules in the morning with a healthy fat source – think yogurt or avocado. These are all fat-soluble molecules, which means they require the presence of dietary fat for optimal absorption and utilization in the body.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using.

Assurance of Purity: highest quality ingredients at cGMP facilities in the US. This means adhering to the most strict, federally regulated quality controls.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:
1. Schultz MB, et al. Why NAD+ Declines during Aging: It’s Destroyed. Cell Metab. 2016. June 14; 23(6): 965–966
2. Saini JS, Corneo B, Miller JD, et al. Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration. Cell Stem Cell 2017;20:635-647.e7. 10.1016/j.stem.2016.12.015
3. Kouassi Nzoughet J, Chao de la Barca JM, Guehlouz K, et al. Nicotinamide deficiency in primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 2019;60(7):2509–2514. doi: 10.1167/iovs.19-27099.
4. Williams PA, Harder JM, Foxworth NE, et al. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science. 2017;355(6326):756–760. doi: 10.1126/science.aal0092.
5. Kouassi Nzoughet J, Chao de la Barca JM, Guehlouz K, et al. Nicotinamide deficiency in primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 2019;60(7):2509–2514. doi: 10.1167/iovs.19-27099.